{"id":2365,"date":"2020-02-29T06:00:49","date_gmt":"2020-02-29T06:00:49","guid":{"rendered":"http:\/\/www.mojemedunka.cz\/?p=2365"},"modified":"2020-03-02T10:03:51","modified_gmt":"2020-03-02T10:03:51","slug":"nemoc-duse-nebo-tela","status":"publish","type":"post","link":"https:\/\/www.mojemedunka.cz\/index.php\/2020\/02\/29\/nemoc-duse-nebo-tela\/","title":{"rendered":"Nemoc du\u0161e nebo t\u011bla?"},"content":{"rendered":"

aneb Nen\u00ed deprese jako deprese<\/em><\/strong> nazvala jeden z mnoha sv\u00fdch zaj\u00edmav\u00fdch \u010dl\u00e1nk\u016f na\u0161e spolupracovnice MUDr. Ludmila Elekov\u00e1<\/strong>. V\u011bnuje se v n\u011bm t\u00e9matu, kter\u00e9 je v dob\u011b st\u00e1le vzr\u016fstaj\u00edc\u00ed spot\u0159eby antidepresiv, l\u00e9k\u016f na span\u00ed, na uklidn\u011bn\u00ed, povzbuzen\u00ed <\/strong>atd. nanejv\u00fd\u0161 aktu\u00e1ln\u00ed. Pokud v\u00e1s \u010dl\u00e1nky t\u00e9to zku\u0161en\u00e9 l\u00e9ka\u0159ky zaj\u00edmaj\u00ed, v\u00fdb\u011br t\u011bch nejzaj\u00edmav\u011bj\u0161\u00edch najdete ve dvou svazc\u00edch edice Knihovni\u010dka Medu\u0148ky<\/em><\/strong> – Bu\u010fme zdrav\u00ed l\u00e9ka\u0159\u016fm navzdory I.a II<\/strong>. MUDr. Elekov\u00e1<\/em> <\/strong>se tak\u00e9 v\u011bnuje tematice o\u010dkov\u00e1n\u00ed<\/strong> – i o tom napsala dv\u011b knihy – tak\u00e9 jsou k dispozici na e-shopu Medu\u0148ky – www.obchodmedunka.cz\u00a0 <\/a>
\nMUDr. Ludmila Elekov\u00e1 bude hostem cyklu Rok zdrav\u00ed s Medu\u0148kou – 3. b\u0159ezna 2020 <\/strong>bude p\u0159edn\u00e1\u0161et a odpov\u00eddat na ot\u00e1zky na t\u00e9ma Zdrav\u00fd mozek po cel\u00fd \u017eivot<\/strong>,
\n7. dubna 2020 <\/strong>se bude v\u011bnovat t\u00e9matu Jak co nejl\u00e9pe zest\u00e1rnout<\/strong>.\u00a0 Za\u010d\u00e1tky od 17 hod, m\u00edsto kon\u00e1n\u00ed Galerie Cesty ke sv\u011btlu Zde\u0148ka Hajn\u00e9ho, Zakou\u0159ilova 955\/9, Praha 4-Chodov.<\/p>\n


\nV\u00fdskyt du\u0161evn\u00edch nemoc\u00ed stoup\u00e1 raketov\u00fdm tempem.<\/strong> Odhaduje se, \u017ee p\u0159ibli\u017en\u011b ka\u017ed\u00fd \u010dtvrt\u00fd \u010dlov\u011bk b\u011bhem \u017eivota onemocn\u00ed du\u0161evn\u00ed nemoc\u00ed. Jak je mo\u017en\u00e9, \u017ee tolik lid\u00ed \u2013 od mal\u00fdch d\u011bt\u00ed po seniory — \u00a0m\u00e1 \u0161patn\u011b funguj\u00edc\u00ed mozek? Skute\u010dn\u011b z\u00e1va\u017en\u00e9, pravd\u011bpodobn\u011b geneticky podm\u00edn\u011bn\u00e9 du\u0161evn\u00ed nemoci, se historicky vyskytovaly \u0159\u00e1dov\u011b jen v\u00a0jednotliv\u00fdch procentech populace, lid\u00e9 nikdy nebyli tak nemocn\u00ed, jako jsou dnes. N\u00e1r\u016fst v\u00fdskytu t\u011bchto nemoc\u00ed mus\u00edme p\u0159i\u010d\u00edst na vrub faktor\u016fm prost\u0159ed\u00ed, \u010dist\u011b geneticky podm\u00edn\u011bn\u00e9 nemoci nem\u011bn\u00ed m\u00edru v\u00fdskytu.<\/p>\n

T\u011blo ovliv\u0148uje du\u0161i?
\n<\/strong>Abychom dob\u0159e pochopili cel\u00fd probl\u00e9m du\u0161evn\u00edch nemoc\u00ed a jejich dopad, mus\u00edme se zamyslet nad ot\u00e1zkou z\u00a0nadpisu. Jsou to skute\u010dn\u00e9 nemoci du\u0161e, n\u011bco, co p\u0159ich\u00e1z\u00ed v\u00a0d\u016fsledku psychick\u00fdch vliv\u016f? Nebo m\u00e1 na vzniku t\u011bchto chorob sv\u016fj pod\u00edl i fyzick\u00fd stav t\u011bla? Je mo\u017en\u00e9, aby vedle psychosomatick\u00fdch nemoc\u00ed existovaly tak\u00e9 nemoci somatopsychick\u00e9? \u017de by naru\u0161en\u00e9 funkce t\u011bla p\u0159\u00edmo ovliv\u0148ovaly funkce du\u0161evn\u00ed? Pokud p\u0159edstava, \u017ee \u010dlov\u011bk m\u016f\u017ee b\u00fdt depresivn\u00ed, \u00fazkostn\u00fd, trp\u011bt nutkav\u00fdch chov\u00e1n\u00edm, schizofreni\u00ed nebo autismem v\u00a0d\u016fsledku naru\u0161en\u00fdch funkc\u00ed t\u011bla, je pro v\u00e1s p\u0159\u00edli\u0161 exotick\u00e1,\u00a0 \u010dt\u011bte d\u00e1le\u2026
\nV\u00a0pediatrii je zn\u00e1m syndrom PANDAS, zkratka znamen\u00e1 \u201epediatrick\u00e1 autoimunn\u00ed neuropsychiatrick\u00e1 porucha spojen\u00e1 se streptokokovou infekc\u00ed.\u201c N\u011bkter\u00e9 d\u011bti infikovan\u00e9 betahemolytick\u00fdm streptokokem skupiny A maj\u00ed rychl\u00fd n\u00e1stup obsedantn\u011b kompulzivn\u00edho chov\u00e1n\u00ed (d\u00e1le OCD). Protil\u00e1tky vznikl\u00e9 p\u0159i reakci na tuto infekci maj\u00ed pravd\u011bpodobn\u011b autoimunn\u00ed \u00fa\u010dinek na funkci baz\u00e1ln\u00edch gangli\u00ed v\u00a0mozku, co\u017e se projevuje zm\u011bnou chov\u00e1n\u00ed. OCD se u t\u011bchto d\u011bt\u00ed logicky nel\u00e9\u010d\u00ed psychofarmaky, ale antibiotiky. Podobn\u00fd p\u0159\u00edpad dosp\u011bl\u00e9 pacientky jsem \u010detla v\u00a0knize dr. Marka Hymana, OCD u n\u00ed vymizela doslova p\u0159es noc po zal\u00e9\u010den\u00ed infekce st\u0159eva antibiotiky. P\u0159ed t\u00edm tr\u00e1vila roky na psychiatrii, doch\u00e1zela na r\u016fzn\u00e9 terapie, brala n\u011bkolikery l\u00e9ky — psychofarmaka a st\u00e1lo j\u00ed to tis\u00edce dolar\u016f a roky zka\u017een\u00e9ho \u017eivota. Tak\u00e9 autistick\u00e9 d\u011bti \u010dasto maj\u00ed v\u00fdrazn\u00e9 zm\u011bny chov\u00e1n\u00ed v\u00a0souvislosti s\u00a0infekc\u00ed.
\nVliv t\u011blesn\u00fdch funkc\u00ed na mozek ukazuje tak\u00e9 jatern\u00ed encefalopatie. Vznik\u00e1 u lid\u00ed se selh\u00e1n\u00edm jater, kdy\u017e dojde k\u00a0infekci za\u017e\u00edvac\u00edho traktu a toxiny produkovan\u00e9 bakteriemi se dostanou do krevn\u00edho ob\u011bhu. Selh\u00e1vaj\u00edc\u00ed j\u00e1tra nejsou schopna je odstranit, proto se dostanou a\u017e do mozku a zp\u016fsob\u00ed stavy zmatenosti a jin\u00e9 p\u0159\u00edznaky. Tento stav se op\u011bt \u00a0nel\u00e9\u010d\u00ed psychofarmaky, ale antibiotiky.
\nSnad ka\u017ed\u00fd z\u00a0n\u00e1s m\u011bl n\u011bkdy vysokou hore\u010dku. Jak v\u00e1m to p\u0159i n\u00ed myslelo? Nem\u011bli jste n\u00e1hodou i vidiny, neblouznili jste?\u00a0 O vliv\u016f r\u016fzn\u00fdch zn\u00e1m\u00fdch toxin\u016f (drog a alkoholu) na du\u0161evn\u00ed funkce nen\u00ed t\u0159eba ps\u00e1t, zn\u00e1me je z\u00a0vlastn\u00ed zku\u0161enosti. Uveden\u00e9 p\u0159\u00edklady jsou jen \u0161pi\u010dkou ledovce vlivu t\u011bla na mysl, slou\u017e\u00ed pouze k\u00a0nastartov\u00e1n\u00ed sm\u011bru my\u0161len\u00ed.
\nJe tedy dob\u0159e zn\u00e1mo, \u017ee r\u016fzn\u00e9 toxiny mohou zm\u011bnit fungov\u00e1n\u00ed mozku, co\u017e se projev\u00ed p\u0159\u00edznaky \u201edu\u0161evn\u00ed nemoci.\u201c Symptomy se projev\u00ed podle toho, kter\u00e1 \u010d\u00e1st mozku je zasa\u017een\u00e1 a jak\u00fdm zp\u016fsobem je zasa\u017een\u00e1. Mozek je dob\u0159e zmapov\u00e1n a je zn\u00e1mo, kter\u00e9 \u010d\u00e1sti mozku \u0159\u00edd\u00ed jeho jednotliv\u00e9 funkce. Z\u00e1le\u017e\u00ed nejen na schopnosti konkr\u00e9tn\u00edho toxinu naru\u0161it ur\u010ditou \u010d\u00e1st mozku, ale i na individu\u00e1ln\u00ed situaci pacienta \u2013 na tom, kde je jeho slab\u00e9 m\u00edsto, kter\u00e1 \u010d\u00e1st mozku ji\u017e byla naru\u0161ena, jak\u00fd je jeho stav v\u00fd\u017eivy apod. V\u00fdsledn\u00e1 symptomatologie je v\u00fdsledkem soub\u011b\u017en\u00e9ho p\u016fsoben\u00ed v\u0161ech faktor\u016f. Na molekul\u00e1rn\u00ed a bun\u011b\u010dn\u00e9 \u00farovni v\u00a0mozku doch\u00e1z\u00ed k\u00a0z\u00e1n\u011btu (infek\u010dn\u00edmu, ale \u010dast\u011bji neinfek\u010dn\u00edmu, zp\u016fsoben\u00e9mu aktivitou imunitn\u00edho syst\u00e9mu), proto\u017ee imunitn\u00ed syst\u00e9m mozku v\u017edy reaguje na infekci v\u00a0t\u011ble. Doch\u00e1z\u00ed k\u00a0naru\u0161en\u00ed hladin neurotransmiter\u016f (glutam\u00e1tu, serotoninu, dopaminu, acetylcholinu a jin\u00fdch), k\u00a0nav\u00e1z\u00e1n\u00ed fale\u0161n\u00fdch neurotransmiter\u016f (potravinov\u00fdch alergen\u016f, toxin\u016f apod.) na receptory, k\u00a0naru\u0161en\u00ed metabolismu neuron\u016f v\u00a0d\u016fsledku nedostatku n\u011bkter\u00fdch \u017eivin nebo p\u016fsoben\u00ed toxin\u016f (rtu\u0165 nap\u0159\u00edklad v\u00fdrazn\u011b naru\u0161uje energetick\u00fd metabolismus nervov\u00fdch bun\u011bk), naru\u0161uje se celkov\u00fd metabolismus nervov\u00fdch bun\u011bk apod.<\/p>\n

Jak n\u00e1s \u0159\u00edd\u00ed mozek?
\n<\/strong>Pov\u011bzme si, kter\u00e9 struktury mozku \u0159\u00edd\u00ed jednotliv\u00e9 funkce a jak se projevuje naru\u0161en\u00ed t\u011bchto struktur.
\nLimbick\u00fd syst\u00e9m \u0159\u00edd\u00ed n\u00e1lady, emoce, agresivitu. Jeho naru\u0161en\u00ed se projevuje poruchami n\u00e1lady, v\u00fdkyvy emoc\u00ed nebo neschopnost\u00ed projevovat emoce a zv\u00fd\u0161en\u00edm agresivity.
\nSp\u00e1nkov\u00e9 laloky \u0159\u00edd\u00ed pam\u011b\u0165, porozum\u011bn\u00ed \u0159e\u010di, sebeovl\u00e1d\u00e1n\u00ed. Jejich porucha se projev\u00ed poruchami u\u010den\u00ed a pam\u011bti, probl\u00e9my s\u00a0porozum\u011bn\u00edm, sn\u00ed\u017een\u00edm sebeovl\u00e1d\u00e1n\u00ed \u2013 v\u00fdbuchy vzteku a destruktivity. Epilepsie v\u00a0oblasti baz\u00e1ln\u00edch gangli\u00ed vede k\u00a0pocit\u016fm depersonalizace, halucinac\u00edm a blud\u016fm.
\nBaz\u00e1ln\u00ed ganglia \u0159\u00edd\u00ed \u00fazkost, strach, motorick\u00e9 funkce. Jejich zv\u00fd\u0161en\u00e1 aktivita se projev\u00ed \u00fazkostnost\u00ed a naru\u0161en\u00edm jemn\u00e9 motoriky.
\nCingul\u00e1rn\u00ed okruh \u0159\u00edd\u00ed p\u0159ep\u00edn\u00e1n\u00ed pozornosti. Jeho naru\u0161en\u00ed vede k nutkav\u00fdm my\u0161lenk\u00e1m a chov\u00e1n\u00ed, pacienti maj\u00ed probl\u00e9m p\u0159esm\u011brovat pozornost, ulp\u00edvaj\u00ed na my\u0161lenk\u00e1ch a \u010dinnostech.
\nPrefront\u00e1ln\u00e1 k\u016fra \u0159\u00edd\u00ed soust\u0159ed\u011bn\u00ed, pl\u00e1nov\u00e1n\u00ed, dokon\u010dov\u00e1n\u00ed v\u011bc\u00ed, pozornost, br\u017ed\u011bn\u00ed impuls\u016f. Jej\u00ed naru\u0161en\u00ed se projevuje netrp\u011blivost\u00ed, hyperaktivitou, neschopnost\u00ed pl\u00e1novat a dokon\u010dit \u00fakoly, impulsivnost\u00ed.
\nPodle toho, kter\u00e1 \u010d\u00e1st mozku je po\u0161kozena, se n\u00e1sledek tohoto po\u0161kozen\u00ed projev\u00ed jako deprese, \u00fazkost, probl\u00e9my s\u00a0pozornost\u00ed, agresivita, impulsivnost, nutkav\u00e9 chov\u00e1n\u00ed, schizofrenie, autismus\u2026Je t\u0159eba si uv\u011bdomit, \u017ee uveden\u00e9 n\u00e1zvy du\u0161evn\u00edch nemoc\u00ed ne\u0159\u00edkaj\u00ed nic o p\u0159\u00ed\u010din\u011b, pouze popisuj\u00ed lokalizaci pot\u00ed\u017e\u00ed…<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

aneb Nen\u00ed deprese jako deprese nazvala jeden z mnoha sv\u00fdch zaj\u00edmav\u00fdch \u010dl\u00e1nk\u016f na\u0161e spolupracovnice MUDr. Ludmila Elekov\u00e1. V\u011bnuje se v n\u011bm t\u00e9matu, kter\u00e9 je v dob\u011b st\u00e1le vzr\u016fstaj\u00edc\u00ed spot\u0159eby antidepresiv, l\u00e9k\u016f na span\u00ed, na uklidn\u011bn\u00ed, povzbuzen\u00ed atd. nanejv\u00fd\u0161 aktu\u00e1ln\u00ed. Pokud v\u00e1s \u010dl\u00e1nky t\u00e9to zku\u0161en\u00e9 l\u00e9ka\u0159ky zaj\u00edmaj\u00ed, v\u00fdb\u011br t\u011bch nejzaj\u00edmav\u011bj\u0161\u00edch najdete ve dvou svazc\u00edch edice Knihovni\u010dka Medu\u0148ky – Bu\u010fme zdrav\u00ed l\u00e9ka\u0159\u016fm navzdory I.a II. MUDr. Elekov\u00e1 se tak\u00e9 v\u011bnuje tematice o\u010dkov\u00e1n\u00ed – i o tom napsala dv\u011b knihy – tak\u00e9 jsou k dispozici na e-shopu Medu\u0148ky – www.obchodmedunka.cz\u00a0 MUDr. Ludmila Elekov\u00e1 bude hostem cyklu Rok zdrav\u00ed s Medu\u0148kou – 3. b\u0159ezna 2020 bude p\u0159edn\u00e1\u0161et a odpov\u00eddat na ot\u00e1zky na t\u00e9ma Zdrav\u00fd mozek po cel\u00fd \u017eivot, 7. dubna 2020 se bude v\u011bnovat t\u00e9matu Jak co nejl\u00e9pe zest\u00e1rnout.\u00a0 Za\u010d\u00e1tky od 17 hod, m\u00edsto kon\u00e1n\u00ed Galerie Cesty ke sv\u011btlu Zde\u0148ka Hajn\u00e9ho, Zakou\u0159ilova 955\/9, Praha 4-Chodov. V\u00fdskyt du\u0161evn\u00edch nemoc\u00ed stoup\u00e1 raketov\u00fdm tempem. Odhaduje se, \u017ee p\u0159ibli\u017en\u011b ka\u017ed\u00fd \u010dtvrt\u00fd \u010dlov\u011bk b\u011bhem \u017eivota onemocn\u00ed du\u0161evn\u00ed nemoc\u00ed. Jak je mo\u017en\u00e9, \u017ee tolik lid\u00ed \u2013 od mal\u00fdch d\u011bt\u00ed po seniory — \u00a0m\u00e1 \u0161patn\u011b funguj\u00edc\u00ed mozek? Skute\u010dn\u011b z\u00e1va\u017en\u00e9, pravd\u011bpodobn\u011b geneticky podm\u00edn\u011bn\u00e9 du\u0161evn\u00ed nemoci, se historicky vyskytovaly \u0159\u00e1dov\u011b jen v\u00a0jednotliv\u00fdch procentech populace, lid\u00e9 nikdy nebyli tak nemocn\u00ed, jako jsou dnes. N\u00e1r\u016fst v\u00fdskytu t\u011bchto nemoc\u00ed mus\u00edme p\u0159i\u010d\u00edst na vrub faktor\u016fm prost\u0159ed\u00ed, \u010dist\u011b geneticky podm\u00edn\u011bn\u00e9 nemoci nem\u011bn\u00ed m\u00edru v\u00fdskytu. T\u011blo ovliv\u0148uje du\u0161i? Abychom dob\u0159e pochopili cel\u00fd probl\u00e9m du\u0161evn\u00edch nemoc\u00ed a jejich dopad, mus\u00edme se zamyslet nad ot\u00e1zkou z\u00a0nadpisu. Jsou to skute\u010dn\u00e9 nemoci du\u0161e, n\u011bco, co p\u0159ich\u00e1z\u00ed v\u00a0d\u016fsledku psychick\u00fdch vliv\u016f? Nebo m\u00e1 na vzniku t\u011bchto chorob sv\u016fj pod\u00edl i fyzick\u00fd stav t\u011bla? Je mo\u017en\u00e9, aby vedle psychosomatick\u00fdch nemoc\u00ed existovaly tak\u00e9 nemoci somatopsychick\u00e9? \u017de by naru\u0161en\u00e9 funkce t\u011bla p\u0159\u00edmo ovliv\u0148ovaly funkce du\u0161evn\u00ed? Pokud p\u0159edstava, \u017ee \u010dlov\u011bk m\u016f\u017ee b\u00fdt depresivn\u00ed, \u00fazkostn\u00fd, trp\u011bt nutkav\u00fdch chov\u00e1n\u00edm, schizofreni\u00ed nebo autismem v\u00a0d\u016fsledku naru\u0161en\u00fdch funkc\u00ed t\u011bla, je pro v\u00e1s p\u0159\u00edli\u0161 exotick\u00e1,\u00a0 \u010dt\u011bte d\u00e1le\u2026 V\u00a0pediatrii je zn\u00e1m syndrom PANDAS, zkratka znamen\u00e1 \u201epediatrick\u00e1 autoimunn\u00ed neuropsychiatrick\u00e1 porucha spojen\u00e1 se streptokokovou infekc\u00ed.\u201c N\u011bkter\u00e9 d\u011bti infikovan\u00e9 betahemolytick\u00fdm streptokokem skupiny A maj\u00ed rychl\u00fd n\u00e1stup obsedantn\u011b kompulzivn\u00edho chov\u00e1n\u00ed (d\u00e1le OCD). Protil\u00e1tky vznikl\u00e9 p\u0159i reakci na tuto infekci maj\u00ed pravd\u011bpodobn\u011b autoimunn\u00ed \u00fa\u010dinek na funkci baz\u00e1ln\u00edch gangli\u00ed v\u00a0mozku, co\u017e se projevuje zm\u011bnou chov\u00e1n\u00ed. OCD se u t\u011bchto d\u011bt\u00ed logicky nel\u00e9\u010d\u00ed psychofarmaky, ale antibiotiky. Podobn\u00fd p\u0159\u00edpad dosp\u011bl\u00e9 pacientky jsem \u010detla v\u00a0knize dr. Marka Hymana, OCD u n\u00ed vymizela doslova p\u0159es noc po zal\u00e9\u010den\u00ed infekce st\u0159eva antibiotiky. P\u0159ed t\u00edm tr\u00e1vila roky na psychiatrii, doch\u00e1zela na r\u016fzn\u00e9 terapie, brala n\u011bkolikery l\u00e9ky — psychofarmaka a st\u00e1lo j\u00ed to tis\u00edce dolar\u016f a roky zka\u017een\u00e9ho \u017eivota. Tak\u00e9 autistick\u00e9 d\u011bti \u010dasto maj\u00ed v\u00fdrazn\u00e9 zm\u011bny chov\u00e1n\u00ed v\u00a0souvislosti s\u00a0infekc\u00ed. Vliv t\u011blesn\u00fdch funkc\u00ed na mozek ukazuje tak\u00e9 jatern\u00ed encefalopatie. Vznik\u00e1 u lid\u00ed se selh\u00e1n\u00edm jater, kdy\u017e dojde k\u00a0infekci za\u017e\u00edvac\u00edho traktu a toxiny produkovan\u00e9 bakteriemi se dostanou do krevn\u00edho ob\u011bhu. Selh\u00e1vaj\u00edc\u00ed j\u00e1tra nejsou schopna je odstranit, proto se dostanou a\u017e do mozku a zp\u016fsob\u00ed stavy zmatenosti a jin\u00e9 p\u0159\u00edznaky. Tento stav se op\u011bt \u00a0nel\u00e9\u010d\u00ed psychofarmaky, ale antibiotiky. Snad ka\u017ed\u00fd z\u00a0n\u00e1s m\u011bl n\u011bkdy vysokou hore\u010dku. Jak v\u00e1m to p\u0159i n\u00ed myslelo? Nem\u011bli jste n\u00e1hodou i vidiny, neblouznili jste?\u00a0 O vliv\u016f r\u016fzn\u00fdch zn\u00e1m\u00fdch toxin\u016f (drog a alkoholu) na du\u0161evn\u00ed funkce nen\u00ed t\u0159eba ps\u00e1t, zn\u00e1me je z\u00a0vlastn\u00ed zku\u0161enosti. Uveden\u00e9 p\u0159\u00edklady jsou jen \u0161pi\u010dkou ledovce vlivu t\u011bla na mysl, slou\u017e\u00ed pouze k\u00a0nastartov\u00e1n\u00ed sm\u011bru my\u0161len\u00ed. Je tedy dob\u0159e zn\u00e1mo, \u017ee r\u016fzn\u00e9 toxiny mohou zm\u011bnit fungov\u00e1n\u00ed mozku, co\u017e se projev\u00ed p\u0159\u00edznaky \u201edu\u0161evn\u00ed nemoci.\u201c Symptomy se projev\u00ed podle toho, kter\u00e1 \u010d\u00e1st mozku je zasa\u017een\u00e1 a jak\u00fdm zp\u016fsobem je zasa\u017een\u00e1. Mozek je dob\u0159e zmapov\u00e1n a je zn\u00e1mo, kter\u00e9 \u010d\u00e1sti mozku \u0159\u00edd\u00ed jeho jednotliv\u00e9 funkce. Z\u00e1le\u017e\u00ed nejen na schopnosti konkr\u00e9tn\u00edho toxinu naru\u0161it ur\u010ditou \u010d\u00e1st mozku, ale i na individu\u00e1ln\u00ed situaci pacienta \u2013 na tom, kde je jeho slab\u00e9 m\u00edsto, kter\u00e1 \u010d\u00e1st mozku ji\u017e byla naru\u0161ena, jak\u00fd je jeho stav v\u00fd\u017eivy apod. V\u00fdsledn\u00e1 symptomatologie je v\u00fdsledkem soub\u011b\u017en\u00e9ho p\u016fsoben\u00ed v\u0161ech faktor\u016f. Na molekul\u00e1rn\u00ed a bun\u011b\u010dn\u00e9 \u00farovni v\u00a0mozku doch\u00e1z\u00ed k\u00a0z\u00e1n\u011btu (infek\u010dn\u00edmu, ale \u010dast\u011bji neinfek\u010dn\u00edmu, zp\u016fsoben\u00e9mu aktivitou imunitn\u00edho syst\u00e9mu), proto\u017ee imunitn\u00ed syst\u00e9m mozku v\u017edy reaguje na infekci v\u00a0t\u011ble. Doch\u00e1z\u00ed k\u00a0naru\u0161en\u00ed hladin neurotransmiter\u016f (glutam\u00e1tu, serotoninu, dopaminu, acetylcholinu a jin\u00fdch), k\u00a0nav\u00e1z\u00e1n\u00ed fale\u0161n\u00fdch neurotransmiter\u016f (potravinov\u00fdch alergen\u016f, toxin\u016f apod.) na receptory, k\u00a0naru\u0161en\u00ed metabolismu neuron\u016f v\u00a0d\u016fsledku nedostatku n\u011bkter\u00fdch \u017eivin nebo p\u016fsoben\u00ed toxin\u016f (rtu\u0165 nap\u0159\u00edklad v\u00fdrazn\u011b naru\u0161uje energetick\u00fd metabolismus nervov\u00fdch bun\u011bk), naru\u0161uje se celkov\u00fd metabolismus nervov\u00fdch bun\u011bk apod. Jak n\u00e1s \u0159\u00edd\u00ed mozek? Pov\u011bzme si, kter\u00e9 struktury mozku \u0159\u00edd\u00ed jednotliv\u00e9 funkce a jak se projevuje naru\u0161en\u00ed t\u011bchto struktur. Limbick\u00fd syst\u00e9m \u0159\u00edd\u00ed n\u00e1lady, emoce, agresivitu. Jeho naru\u0161en\u00ed se projevuje poruchami n\u00e1lady, v\u00fdkyvy emoc\u00ed nebo neschopnost\u00ed projevovat emoce a zv\u00fd\u0161en\u00edm agresivity. Sp\u00e1nkov\u00e9 laloky \u0159\u00edd\u00ed pam\u011b\u0165, porozum\u011bn\u00ed \u0159e\u010di, sebeovl\u00e1d\u00e1n\u00ed. Jejich porucha se projev\u00ed poruchami u\u010den\u00ed a pam\u011bti, probl\u00e9my s\u00a0porozum\u011bn\u00edm, sn\u00ed\u017een\u00edm sebeovl\u00e1d\u00e1n\u00ed \u2013 v\u00fdbuchy vzteku a destruktivity. Epilepsie v\u00a0oblasti baz\u00e1ln\u00edch gangli\u00ed vede k\u00a0pocit\u016fm depersonalizace, halucinac\u00edm a blud\u016fm. Baz\u00e1ln\u00ed ganglia \u0159\u00edd\u00ed \u00fazkost, strach, motorick\u00e9 funkce. Jejich zv\u00fd\u0161en\u00e1 aktivita se projev\u00ed \u00fazkostnost\u00ed a naru\u0161en\u00edm jemn\u00e9 motoriky. Cingul\u00e1rn\u00ed okruh \u0159\u00edd\u00ed p\u0159ep\u00edn\u00e1n\u00ed pozornosti. Jeho naru\u0161en\u00ed vede k nutkav\u00fdm my\u0161lenk\u00e1m a chov\u00e1n\u00ed, pacienti maj\u00ed probl\u00e9m p\u0159esm\u011brovat pozornost, ulp\u00edvaj\u00ed na my\u0161lenk\u00e1ch a \u010dinnostech. Prefront\u00e1ln\u00e1 k\u016fra \u0159\u00edd\u00ed soust\u0159ed\u011bn\u00ed, pl\u00e1nov\u00e1n\u00ed, dokon\u010dov\u00e1n\u00ed v\u011bc\u00ed, pozornost, br\u017ed\u011bn\u00ed impuls\u016f. Jej\u00ed naru\u0161en\u00ed se projevuje netrp\u011blivost\u00ed, hyperaktivitou, neschopnost\u00ed pl\u00e1novat a dokon\u010dit \u00fakoly, impulsivnost\u00ed. Podle toho, kter\u00e1 \u010d\u00e1st mozku je po\u0161kozena, se n\u00e1sledek tohoto po\u0161kozen\u00ed projev\u00ed jako deprese, \u00fazkost, probl\u00e9my s\u00a0pozornost\u00ed, agresivita, impulsivnost, nutkav\u00e9 chov\u00e1n\u00ed, schizofrenie, autismus\u2026Je t\u0159eba si uv\u011bdomit, \u017ee uveden\u00e9 n\u00e1zvy du\u0161evn\u00edch nemoc\u00ed ne\u0159\u00edkaj\u00ed nic o p\u0159\u00ed\u010din\u011b, pouze popisuj\u00ed lokalizaci pot\u00ed\u017e\u00ed…  <\/p>\n","protected":false},"author":3,"featured_media":2376,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,10],"tags":[],"class_list":["post-2365","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medunka","category-zdravi"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/posts\/2365","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/comments?post=2365"}],"version-history":[{"count":7,"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/posts\/2365\/revisions"}],"predecessor-version":[{"id":2450,"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/posts\/2365\/revisions\/2450"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/media\/2376"}],"wp:attachment":[{"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/media?parent=2365"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/categories?post=2365"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mojemedunka.cz\/index.php\/wp-json\/wp\/v2\/tags?post=2365"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}